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Ketosynthase from module 6 of the bacillaene synthase from bacillus subtilis 168

Analyse Ketosynthase from module 6 of the bacillaene synthase from bacillus subtilis 168 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5ERF
Type: protein
Length: 1,113 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Polyketide synthase pksl
UniProt: Q05470
Pockets: 15 · best druggability 0.80

Structure

x-ray diffraction · 2 distinct chains · 39% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Polyketide synthase pksl	protein	553	39% helix, 21% strand	Q05470
B	Polyketide synthase pksl	protein	560	39% helix, 20% strand	Q05470

Pockets

15 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1019	0.80	0.81	85	empty
2	640	0.72	0.79	61	empty
3	167	0.68	0.87	31	empty
4	164	0.67	0.87	28	empty
5	560	0.67	0.77	52	empty

Interfaces

1 interface between chains.

A–B · 1941 Å² buried · 24 hydrogen bonds · protein-protein

Compared structures

5ERF · Ketosynthase from module 6 of the bacillaene synthase from Bacillus subtilis 168 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q05470
Elsewhere: RCSB PDB 5ERF · PDBe 5ERF · UniProt Q05470

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