Research workbench
Crystal structure of mouse unkempt zinc fingers 4-6 (ZNF4-6), bound to RNA
Analyse Crystal structure of mouse unkempt zinc fingers 4-6 (ZNF4-6), bound to RNA in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5ELK
- Type
- protein + RNA
- Length
- 125 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ring finger protein unkempt homolog; RNA
- UniProt
- Q8BL48
- Ligands
- ZN
- Pockets
- 1 · best druggability 0.38
Structure
x-ray diffraction · 2 distinct chains · 20% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ring finger protein unkempt homolog | protein | 121 | 20% helix, 8% strand | Q8BL48 |
| R | RNA | rna | 4 | — | — |
Ligands and binding sites
- ZN · Zinc ion · metal · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 73 | 0.38 | 0.78 | 19 | empty |
Interfaces
1 interface between chains.
- A–R · 613 Ų buried · 17 hydrogen bonds · protein-nucleic
Compared structures
- 5ELK · Crystal structure of mouse Unkempt zinc fingers 4-6 (ZnF4-6), bound to RNA · the same entry in another collection · chain A against A, TM-score 1.00
- Q8BL48 · AlphaFold monomer V2.0 prediction for ring finger protein unkempt homolog (Q8BL48) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8BL48
- Elsewhere: RCSB PDB 5ELK · PDBe 5ELK · UniProt Q8BL48
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