Research workbench
Crystal structure of tRNA dependent lantibiotic dehydratase mibb from microbispora sp. 107891
Analyse Crystal structure of tRNA dependent lantibiotic dehydratase mibb from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5EHK
- Type
- protein
- Length
- 2,072 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lantibiotic dehydratase
- UniProt
- E2IHB7
- Pockets
- 20 · best druggability 0.78
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Lantibiotic dehydratase | protein | 1036 | 44% helix, 18% strand | E2IHB7 |
Pockets
20 pockets found on a 1 Å grid, 14 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 974 | 0.78 | 0.80 | 109 | empty |
| 2 | 1012 | 0.76 | 0.78 | 92 | empty |
| 3 | 116 | 0.76 | 0.95 | 38 | empty |
| 4 | 588 | 0.72 | 0.80 | 69 | empty |
| 5 | 79 | 0.72 | 0.96 | 29 | empty |
Interfaces
1 interface between chains.
- A–B · 3130 Ų buried · 34 hydrogen bonds · protein-protein
Compared structures
- 5EHK · Crystal structure of tRNA dependent lantibiotic dehydratase MibB from Microbispora sp.… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt E2IHB7
- Elsewhere: RCSB PDB 5EHK · PDBe 5EHK · UniProt E2IHB7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.