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Structure of candida albicans trehalose-6-phosphate phosphatase N- terminal domain

Analyse Structure of candida albicans trehalose-6-phosphate phosphatase N- terminal… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5DXF
Type: protein
Length: 928 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Trehalose-6-phosphate phosphatase
EC: 2.4.1.15
UniProt: Q5AI14
Pockets: 10 · best druggability 0.79

Structure

x-ray diffraction · 2 distinct chains · 46% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Trehalose-6-phosphate phosphatase (EC 2.4.1.15)	protein	460	46% helix, 16% strand	Q5AI14
B	Trehalose-6-phosphate phosphatase (EC 2.4.1.15)	protein	468	45% helix, 17% strand	Q5AI14

Pockets

10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	520	0.79	0.86	59	empty
2	1017	0.79	0.81	85	empty
3	662	0.77	0.82	62	empty
4	422	0.65	0.78	50	empty
5	90	0.51	0.83	16	empty

Interfaces

1 interface between chains.

A–B · 681 Å² buried · 1 hydrogen bond · protein-protein

Compared structures

5DXF · Structure of Candida albicans trehalose-6-phosphate phosphatase N-terminal domain · the same entry in another collection · chain B against B, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5AI14
Elsewhere: RCSB PDB 5DXF · PDBe 5DXF · UniProt Q5AI14

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