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The fatty acid-responsive fadr repressor of vibrio alginolyticus complex with palmitoyl-CoA

Analyse The fatty acid-responsive fadr repressor of vibrio alginolyticus complex with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5DV5
Type: protein
Length: 534 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Gntr family transcriptional regulator
UniProt: A0A0G9LXQ8
Ligands: PKZ
Pockets: 4 · best druggability 0.90

Structure

x-ray diffraction · 1 distinct chain · 69% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Gntr family transcriptional regulator	protein	267	69% helix, 2% strand	A0A0G9LXQ8

Ligands and binding sites

PKZ · Palmitoyl-CoA · ligand · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1194	0.90	0.91	115	PKZ
2	243	0.51	0.75	20	empty
3	52	0.35	0.79	13	empty
4	56	0.27	0.73	11	empty

Interfaces

1 interface between chains.

A–B · 1245 Å² buried · 10 hydrogen bonds · protein-protein

Compared structures

5DV5 · The fatty acid-responsive FadR repressor of Vibrio alginolyticus complex with… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0G9LXQ8
Elsewhere: RCSB PDB 5DV5 · PDBe 5DV5 · UniProt A0A0G9LXQ8

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