Research workbench
Crystal structure of the drosophila GLUR1A ligand binding domain complex with glutamate
Analyse Crystal structure of the drosophila GLUR1A ligand binding domain complex with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5DT6
- Type
- protein
- Length
- 266 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glutamate receptor 1
- UniProt
- Q03445
- Ligands
- GLU
- Pockets
- 2 · best druggability 0.41
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glutamate receptor 1 | protein | 266 | 37% helix, 22% strand | Q03445 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 62 | 0.41 | 0.81 | 24 | GOL |
| 2 | 54 | 0.28 | 0.75 | 9 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 5DT6 · Crystal structure of the Drosophila GluR1A ligand binding domain complex with glutamate · the same entry in another collection · chain A against A, TM-score 1.00
- Q03445 · AlphaFold monomer V2.0 prediction for glutamate receptor 1 (Q03445) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q03445
- Elsewhere: RCSB PDB 5DT6 · PDBe 5DT6 · UniProt Q03445
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