Research workbench

Crystal structure of TRANCE/RANKL cytokine.

Analyse Crystal structure of TRANCE/RANKL cytokine. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1JTZ
Type: protein
Length: 465 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tumor necrosis factor ligand superfamily member 11
UniProt: O35235
Pockets: 2 · best druggability 0.72

Structure

x-ray diffraction · 1 distinct chain · 4% helix, 55% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
X, Y, Z	Tumor necrosis factor ligand superfamily member 11	protein	155	4% helix, 55% strand	O35235

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	53	0.72	0.99	13	empty
2	185	0.55	0.80	25	empty

Interfaces

3 interfaces between chains.

X–Y · 1109 Å² buried · 17 hydrogen bonds · protein-protein
X–Z · 1098 Å² buried · 17 hydrogen bonds · protein-protein
Y–Z · 1085 Å² buried · 17 hydrogen bonds · protein-protein

Compared structures

1JTZ · Crystal structure of TRANCE/RANKL cytokine. · the same entry in another collection · chain X against X, TM-score 1.00
O35235 · AlphaFold monomer V2.0 prediction for tumor necrosis factor ligand superfamily member 11… · a predicted model of the same protein · chain X against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O35235
Elsewhere: RCSB PDB 1JTZ · PDBe 1JTZ · UniProt O35235

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.