Research workbench

Apo form of the quorum sensor nprr from B. thuringiensis

Analyse Apo form of the quorum sensor nprr from B. thuringiensis in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5DBK
Type: protein
Length: 707 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transcriptional REGULATOR/TPR domain protein
UniProt: M1Q3P9
Pockets: 6 · best druggability 0.80

Structure

x-ray diffraction · 2 distinct chains · 80% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transcriptional REGULATOR/TPR domain protein	protein	355	81% helix, 0% strand	M1Q3P9
B	Transcriptional REGULATOR/TPR domain protein	protein	352	80% helix, 0% strand	M1Q3P9

Pockets

6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	941	0.80	0.81	76	empty
2	497	0.62	0.75	41	empty
3	251	0.58	0.79	33	empty
4	216	0.51	0.76	31	empty
5	87	0.42	0.79	17	empty

Interfaces

1 interface between chains.

A–B · 1156 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

5DBK · apo form of the quorum sensor NprR from B. thuringiensis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt M1Q3P9
Elsewhere: RCSB PDB 5DBK · PDBe 5DBK · UniProt M1Q3P9

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