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RNA octamer containing (S)-5' methyl, 2'-F U.

Analyse RNA octamer containing (S)-5' methyl, 2'-F U. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
5D8T
Type
RNA
Length
16 nucleotides
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
RNA oligonucleotide containing (S)-C5'-me-2'-fu
Ligands
NCO
Pockets
1 · best druggability 0.34

Structure

x-ray diffraction · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, BRNA oligonucleotide containing (S)-C5'-me-2'-furna8——

Ligands and binding sites

  • NCO · Cobalt hexammine(iii) · ligand · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11040.340.7412NCO

Interfaces

1 interface between chains.

  • A–B · 394 Ų buried · 33 hydrogen bonds · nucleic-nucleic

Modifications

Observed in the structure: 4 modified (nucleotide modification).

Compared structures

  • 5D8T · RNA octamer containing (S)-5' methyl, 2'-F U. · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

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