Research workbench
Fitting of L11 protein and elongation factor G (ef-G) in the cryo-EM MAP of E. COLI 70S ribosome bound with ef-G, GDP and fusidic acid
Analyse Fitting of L11 protein and elongation factor G (ef-G) in the cryo-EM MAP of E.… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1JQM
- Type
- protein
- Length
- 824 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 50S ribosomal protein L11; Elongation factor G
- UniProt
- P29395, P13551
- Pockets
- 3 · best druggability 0.36
Structure
electron microscopy · 2 distinct chains · 0% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 50S ribosomal protein L11 | protein | 133 | 0% helix, 0% strand | P29395 |
| B | Elongation factor G | protein | 691 | 0% helix, 0% strand | P13551 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 92 | 0.36 | 0.73 | 28 | empty |
| 2 | 69 | 0.33 | 0.73 | 18 | empty |
| 3 | 54 | 0.29 | 0.73 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 38 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 1JQM · Fitting of L11 protein and elongation factor G (EF-G) in the cryo-em map of e. coli 70S… · the same entry in another collection · chain A against A, TM-score 1.00
- P13551 · AlphaFold monomer V2.0 prediction for elongation factor G (P13551) · a predicted model of the same protein · chain B against A, TM-score 0.73
- P29395 · AlphaFold monomer V2.0 prediction for 50S ribosomal protein L11 (P29395) · a predicted model of the same protein · chain A against A, TM-score 0.63
- 1OLN · Model for thiostrepton antibiotic binding to L11 substrate from 50S ribosomal RNA · a predicted model of the same protein · chain A against A, TM-score 0.63
- 1OLN · Model for thiostrepton antibiotic binding to L11 substrate from 50S ribosomal RNA · a predicted model of the same protein · chain A against A, TM-score 0.63
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P29395
- Every structure of UniProt P13551
- Elsewhere: RCSB PDB 1JQM · PDBe 1JQM · UniProt P29395 · UniProt P13551
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