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Crystal structure of yeast GGA1_GAE domain-C2221

Analyse Crystal structure of yeast GGA1_GAE domain-C2221 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5CN2
Type: protein
Length: 229 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: ADP-ribosylation factor-binding protein GGA1
UniProt: Q06336
Pockets: 1 · best druggability 0.58

Structure

x-ray diffraction · 2 distinct chains · 3% helix, 59% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ADP-ribosylation factor-binding protein GGA1	protein	115	3% helix, 62% strand	Q06336
B	ADP-ribosylation factor-binding protein GGA1	protein	114	3% helix, 57% strand	Q06336

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	318	0.58	0.77	38	empty

Interfaces

1 interface between chains.

A–B · 279 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

5CN2 · Crystal structure of yeast GGA1_GAE domain-C2221 · the same entry in another collection · chain A against A, TM-score 1.00
Q06336 · AlphaFold monomer V2.0 prediction for ADP-ribosylation factor-binding protein GGA1… · a predicted model of the same protein · chain B against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q06336
Elsewhere: RCSB PDB 5CN2 · PDBe 5CN2 · UniProt Q06336

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