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Crystal structure of human tob in complex with inhibitor fragment 1

Analyse Crystal structure of human tob in complex with inhibitor fragment 1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5CI8
Type: protein
Length: 117 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein TOB1
UniProt: P50616
Ligands: 53Y

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein TOB1	protein	117	41% helix, 21% strand	P50616

Ligands and binding sites

53Y · pyrrolo[1,2-a]quinoxalin-4(5H)-one · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 1 covalent (covalent ligand).

Compared structures

5CI8 · Crystal structure of human Tob in complex with inhibitor fragment 1 · the same entry in another collection · chain A against A, TM-score 1.00
P50616 · AlphaFold monomer V2.0 prediction for protein TOB1 (P50616) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P50616
Elsewhere: RCSB PDB 5CI8 · PDBe 5CI8 · UniProt P50616

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