Research workbench

Structure of mouse ADP-dependent glucokinase

Analyse Structure of mouse ADP-dependent glucokinase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5CCF
Type: protein
Length: 446 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: ADP-dependent glucokinase
EC: 2.7.1.147
UniProt: Q8VDL4
Pockets: 4 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 37% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ADP-dependent glucokinase (EC 2.7.1.147)	protein	446	37% helix, 22% strand	Q8VDL4

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	581	0.66	0.77	54	empty
2	220	0.50	0.76	31	empty
3	114	0.46	0.79	21	empty
4	89	0.40	0.77	13	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

5CCF · Structure of Mouse ADP-Dependent Glucokinase · the same entry in another collection · chain A against A, TM-score 1.00
Q8VDL4 · AlphaFold monomer V2.0 prediction for ADP-dependent glucokinase (Q8VDL4) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8VDL4
Elsewhere: RCSB PDB 5CCF · PDBe 5CCF · UniProt Q8VDL4

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.