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Crystal structure of conjoint pyrococcus furiosus L-asparaginase at 37 degree C

Analyse Crystal structure of conjoint pyrococcus furiosus L-asparaginase at 37 degree C in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5CBP
Type: protein
Length: 309 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: L-asparaginase
UniProt: Q8TZE8

Structure

x-ray diffraction · 2 distinct chains · 31% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	L-asparaginase	protein	182	29% helix, 31% strand	Q8TZE8
B	L-asparaginase	protein	127	35% helix, 14% strand	Q8TZE8

Ligands and binding sites

GOL · Glycerol · additive · 6 copies · chains A, B
IPA · Isopropyl alcohol · additive · 3 copies · chains A
FLC · Citrate anion · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 968 Å² buried · 17 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

5CBP · Crystal Structure of Conjoint Pyrococcus furiosus L-asparaginase at 37 degree C · the same entry in another collection · chain A against A, TM-score 1.00
Q8TZE8 · AlphaFold monomer V2.0 prediction for L-asparaginase (Q8TZE8) · a predicted model of the same protein · chain B against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8TZE8
Elsewhere: RCSB PDB 5CBP · PDBe 5CBP · UniProt Q8TZE8

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