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5'-monophosphate wt guanine riboswitch bound to hypoxanthine.

Analyse 5'-monophosphate wt guanine riboswitch bound to hypoxanthine. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
5C7U
Type
RNA
Length
67 nucleotides
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
5'-monophosphate wt guanine riboswitch
Ligands
NCO, HPA
Pockets
2 · best druggability 0.67

Structure

x-ray diffraction · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
B5'-monophosphate wt guanine riboswitchrna67——

Ligands and binding sites

  • NCO · Cobalt hexammine(iii) · ligand · 7 copies · chains B
  • HPA · Hypoxanthine · ligand · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
18810.670.7536NCO
21180.390.7619HPA

Compared structures

  • 5C7U · 5'-monophosphate wt Guanine Riboswitch bound to hypoxanthine. · the same entry in another collection · chain B against B, TM-score 1.00

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