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The C-jun N-terminal kinase (JNK3S) complexed with mgamp-pnp

Analyse The C-jun N-terminal kinase (JNK3S) complexed with mgamp-pnp in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1JNK
Type: protein
Length: 346 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: C-jun N-terminal kinase
EC: 2.7.1.-
UniProt: P53779
Ligands: ANP, MG
Pockets: 1 · best druggability 0.70

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	C-jun N-terminal kinase (EC 2.7.1.-)	protein	346	38% helix, 17% strand	P53779

Ligands and binding sites

ANP · Phosphoaminophosphonic acid-adenylate ester · ligand · chains A
MG · Magnesium ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	525	0.70	0.79	53	MG, ANP

Compared structures

1JNK · The C-jun N-terminal kinase (JNK3S) complexed with mgamp-pnp · the same entry in another collection · chain A against A, TM-score 1.00
P53779 · AlphaFold monomer V2.0 prediction for mitogen-activated protein kinase 10 (P53779) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P53779
Elsewhere: RCSB PDB 1JNK · PDBe 1JNK · UniProt P53779

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