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Crystal structure of the zp-C domain of mouse ZP2

Analyse Crystal structure of the zp-C domain of mouse ZP2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5BUP
Type: protein
Length: 159 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Zona pellucida sperm-binding protein 2
UniProt: P20239
Pockets: 2 · best druggability 0.37

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Zona pellucida sperm-binding protein 2	protein	159	6% helix, 44% strand	P20239

Ligands and binding sites

ACT · Acetate ion · additive · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	88	0.37	0.76	19	empty
2	51	0.24	0.73	14	ACT

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

5BUP · Crystal structure of the ZP-C domain of mouse ZP2 · the same entry in another collection · chain A against A, TM-score 1.00
P20239 · AlphaFold monomer V2.0 prediction for zona pellucida sperm-binding protein 2 (P20239) · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P20239
Elsewhere: RCSB PDB 5BUP · PDBe 5BUP · UniProt P20239

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