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Solution NMR structure of a 16-mer DNA duplex containing quadruple gc mismatches showing staggered base pairing, and consequent rescue of canonical double helical characteristics

Analyse Solution NMR structure of a 16-mer DNA duplex containing quadruple gc… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
5B81
Type
DNA
Length
32 nucleotides
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
DNA (5'-D(*GP*CP*GP*CP*AP*TP*GP*CP*GP*CP*TP*AP*CP*GP*CP*G)- 3'); DNA…

Structure

solution nmr · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA (5'-D(*GP*CP*GP*CP*AP*TP*GP*CP*GP*CP*TP*AP*CP*GP*CP*G)- 3')dna16——
BDNA (5'-D(*CP*GP*CP*GP*TP*AP*CP*GP*CP*GP*AP*TP*GP*CP*GP*C)- 3')dna16——

Interfaces

1 interface between chains.

  • A–B · 776 Ų buried · 69 hydrogen bonds · nucleic-nucleic

Compared structures

  • 5B81 · Solution NMR structure of a 16-mer DNA duplex containing quadruple GC mismatches showing… · the same entry in another collection · chain A against A, TM-score 1.00

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