Research workbench

OXYR2 E204G mutant regulatory domain from vibrio vulnificus (sulfate- bound)

Analyse OXYR2 E204G mutant regulatory domain from vibrio vulnificus (sulfate- bound) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5B7D
Type: protein
Length: 425 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lysr family transcriptional regulator
UniProt: A0A087I947
Ligands: SO4
Pockets: 2 · best druggability 0.50

Structure

x-ray diffraction · 2 distinct chains · 32% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lysr family transcriptional regulator	protein	212	33% helix, 26% strand	A0A087I947
B	Lysr family transcriptional regulator	protein	213	32% helix, 26% strand	A0A087I947

Ligands and binding sites

SO4 · Sulfate ion · ion · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	295	0.50	0.73	38	empty
2	267	0.48	0.73	30	empty

Interfaces

1 interface between chains.

A–B · 314 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

5B7D · OxyR2 E204G mutant regulatory domain from Vibrio vulnificus (sulfate-bound) · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A087I947
Elsewhere: RCSB PDB 5B7D · PDBe 5B7D · UniProt A0A087I947

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