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Crystal structure of a bacterial homologue of iron transporter ferroportin in outward-facing state

Analyse Crystal structure of a bacterial homologue of iron transporter ferroportin in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5AYN
Type: protein
Length: 405 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Solute carrier family 39 (iron-regulated transporter)
UniProt: Q6MLJ0
Ligands: K
Pockets: 2 · best druggability 0.81

Structure

x-ray diffraction · 1 distinct chain · 85% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Solute carrier family 39 (iron-regulated transporter)	protein	405	85% helix, 0% strand	Q6MLJ0

Ligands and binding sites

K · Potassium ion · metal · chains A
OLC · (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate · additive · 9 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	958	0.81	0.83	74	empty
2	52	0.37	0.80	17	empty

Compared structures

5AYN · Crystal structure of a bacterial homologue of iron transporter ferroportin in… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6MLJ0
Elsewhere: RCSB PDB 5AYN · PDBe 5AYN · UniProt Q6MLJ0

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