Research workbench
Sequence iankedkad inserted between GCN4 adaptors - structure A9B grey
Analyse Sequence iankedkad inserted between GCN4 adaptors - structure A9B grey in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5APV
- Type
- protein
- Length
- 408 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- General control protein GCN4
- UniProt
- P03069
- Pockets
- 2 · best druggability 0.42
Structure
x-ray diffraction · 4 distinct chains · 88% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | General control protein GCN4 | protein | 70 | 86% helix, 3% strand | P03069 |
| B, E, F | General control protein GCN4 | protein | 67 | 91% helix, 3% strand | P03069 |
| C | General control protein GCN4 | protein | 69 | 90% helix, 3% strand | P03069 |
| D | General control protein GCN4 | protein | 68 | 85% helix, 3% strand | P03069 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 131 | 0.42 | 0.76 | 21 | empty |
| 2 | 114 | 0.38 | 0.75 | 24 | empty |
Interfaces
9 interfaces between chains.
- B–C · 1594 Ų buried · 13 hydrogen bonds · protein-protein
- D–E · 1550 Ų buried · 9 hydrogen bonds · protein-protein
- A–B · 1525 Ų buried · 9 hydrogen bonds · protein-protein
- E–F · 1524 Ų buried · 9 hydrogen bonds · protein-protein
- A–C · 1462 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 5APV · Sequence IANKEDKAD inserted between GCN4 adaptors - Structure A9b grey · the same entry in another collection · chain F against F, TM-score 1.00
- P03069 · AlphaFold monomer V2.0 prediction for general control transcription factor GCN4 (P03069) · a predicted model of the same protein · chain B against A, TM-score 0.59
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03069
- Elsewhere: RCSB PDB 5APV · PDBe 5APV · UniProt P03069
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