Research workbench
Structure of the SAM-dependent RRNA:ACP-transferase TSR3 from S. solfataricus
Analyse Structure of the SAM-dependent RRNA:ACP-transferase TSR3 from S. solfataricus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5AP8
- Type
- protein
- Length
- 464 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- TSR3
- EC
- 2.5.1.-
- UniProt
- Q9UWV6
- Pockets
- 3 · best druggability 0.81
Structure
x-ray diffraction · 3 distinct chains · 41% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | TSR3 (EC 2.5.1.-) | protein | 151 | 39% helix, 14% strand | Q9UWV6 |
| B | TSR3 (EC 2.5.1.-) | protein | 157 | 42% helix, 13% strand | Q9UWV6 |
| C | TSR3 (EC 2.5.1.-) | protein | 156 | 43% helix, 13% strand | Q9UWV6 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 920 | 0.81 | 0.83 | 77 | empty |
| 2 | 594 | 0.68 | 0.77 | 62 | empty |
| 3 | 69 | 0.30 | 0.73 | 12 | empty |
Interfaces
3 interfaces between chains.
- B–C · 586 Ų buried · 11 hydrogen bonds · protein-protein
- A–B · 519 Ų buried · 4 hydrogen bonds · protein-protein
- A–C · 110 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 5AP8 · Structure of the SAM-dependent rRNA:acp-transferase Tsr3 from S. solfataricus · the same entry in another collection · chain C against C, TM-score 1.00
- Q9UWV6 · AlphaFold monomer V2.0 prediction for 16S rRNA aminocarboxypropyltransferase (Q9UWV6) · a predicted model of the same protein · chain C against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UWV6
- Elsewhere: RCSB PDB 5AP8 · PDBe 5AP8 · UniProt Q9UWV6
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.