Research workbench
Crystal structure of ligand-free nadr
Analyse Crystal structure of ligand-free nadr in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5AIQ
- Type
- protein
- Length
- 521 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcriptional regulator, marr family
- UniProt
- Q7DD70
- Pockets
- 7 · best druggability 0.73
Structure
x-ray diffraction · 4 distinct chains · 74% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcriptional regulator, marr family | protein | 131 | 73% helix, 7% strand | Q7DD70 |
| B | Transcriptional regulator, marr family | protein | 132 | 77% helix, 8% strand | Q7DD70 |
| C | Transcriptional regulator, marr family | protein | 130 | 74% helix, 8% strand | Q7DD70 |
| D | Transcriptional regulator, marr family | protein | 128 | 75% helix, 7% strand | Q7DD70 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 631 | 0.73 | 0.80 | 43 | empty |
| 2 | 52 | 0.69 | 0.97 | 19 | empty |
| 3 | 265 | 0.60 | 0.79 | 31 | empty |
| 4 | 277 | 0.52 | 0.75 | 32 | empty |
| 5 | 130 | 0.47 | 0.78 | 23 | empty |
Interfaces
4 interfaces between chains.
- C–D · 2418 Ų buried · 15 hydrogen bonds · protein-protein
- A–B · 2370 Ų buried · 23 hydrogen bonds · protein-protein
- A–D · 611 Ų buried · 14 hydrogen bonds · protein-protein
- A–C · 354 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 5AIQ · Crystal structure of ligand-free NadR · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7DD70
- Elsewhere: RCSB PDB 5AIQ · PDBe 5AIQ · UniProt Q7DD70
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.