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Crystal structure of the lotus domain (aa 139-240) of drosophila oskar in P65

Analyse Crystal structure of the lotus domain (aa 139-240) of drosophila oskar in P65 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5A48
Type: protein
Length: 180 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Maternal effect protein oskar
UniProt: P25158
Pockets: 1 · best druggability 0.34

Structure

x-ray diffraction · 2 distinct chains · 38% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Maternal effect protein oskar	protein	84	40% helix, 13% strand	P25158
B	Maternal effect protein oskar	protein	96	36% helix, 11% strand	P25158

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	117	0.34	0.72	24	empty

Interfaces

1 interface between chains.

A–B · 769 Å² buried · 22 hydrogen bonds · protein-protein

Compared structures

5A48 · Crystal structure of the LOTUS domain (aa 139-240) of Drosophila Oskar in P65 · the same entry in another collection · chain A against A, TM-score 1.00
P25158 · AlphaFold monomer V2.0 prediction for maternal effect protein oskar (P25158) · a predicted model of the same protein · chain A against A, TM-score 0.88

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P25158
Elsewhere: RCSB PDB 5A48 · PDBe 5A48 · UniProt P25158

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