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Dictyostelium discoideum cellobiohydrolase CEL7A apo structure

Analyse Dictyostelium discoideum cellobiohydrolase CEL7A apo structure in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4ZZQ
Type: protein
Length: 437 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cellulose 1,4-beta-cellobiosidase
EC: 3.2.1.176
UniProt: Q55FE6
Ligands: NAG
Pockets: 2 · best druggability 0.82

Structure

x-ray diffraction · 1 distinct chain · 12% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cellulose 1,4-beta-cellobiosidase (EC 3.2.1.176)	protein	437	12% helix, 34% strand	Q55FE6

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
PEG · Di(hydroxyethyl)ether · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	816	0.82	0.85	79	PEG
2	53	0.72	0.99	22	empty

Modifications

Observed in the structure: 9 disulfide, 1 glycan, 1 modified (disulfide, N-glycosylation, cyclization).

Compared structures

4ZZQ · Dictyostelium discoideum cellobiohydrolase Cel7A apo structure · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q55FE6
Elsewhere: RCSB PDB 4ZZQ · PDBe 4ZZQ · UniProt Q55FE6

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