Research workbench
Crystal structure of beta-hydroxyacyl-acyl carrier protein dehydratase (fabz) from candidatus asiaticum
Analyse Crystal structure of beta-hydroxyacyl-acyl carrier protein dehydratase (fabz)… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4ZW0
- Type
- protein
- Length
- 428 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 3-hydroxyacyl-[acyl-carrier-protein] dehydratase fabz
- EC
- 4.2.1.59
- UniProt
- C6XFU0
- Pockets
- 4 · best druggability 0.77
Structure
x-ray diffraction · 2 distinct chains · 21% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase fabz (EC 4.2.1.59) | protein | 142 | 21% helix, 39% strand | C6XFU0 |
| C | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase fabz (EC 4.2.1.59) | protein | 144 | 21% helix, 40% strand | C6XFU0 |
Pockets
4 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 120 | 0.77 | 0.96 | 43 | empty |
| 2 | 136 | 0.76 | 0.94 | 45 | empty |
| 3 | 82 | 0.62 | 0.89 | 18 | empty |
| 4 | 80 | 0.58 | 0.88 | 27 | empty |
Interfaces
3 interfaces between chains.
- B–C · 1391 Ų buried · 21 hydrogen bonds · protein-protein
- A–B · 1153 Ų buried · 20 hydrogen bonds · protein-protein
- A–C · 24 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 4ZW0 · Crystal structure of beta-Hydroxyacyl-acyl carrier protein dehydratase (FabZ) from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C6XFU0
- Elsewhere: RCSB PDB 4ZW0 · PDBe 4ZW0 · UniProt C6XFU0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.