Research workbench
Crystal structure of the artificial alpharep-7 OCTARELLINV.1 complex
Analyse Crystal structure of the artificial alpharep-7 OCTARELLINV.1 complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4ZV6
- Type
- protein
- Length
- 433 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Alpharep-7; Octarellin V.1
- Pockets
- 5 · best druggability 0.73
Structure
x-ray diffraction · 2 distinct chains · 67% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Alpharep-7 | protein | 278 | 78% helix, 0% strand | — |
| B | Octarellin V.1 | protein | 155 | 48% helix, 15% strand | — |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 473 | 0.73 | 0.81 | 35 | empty |
| 2 | 73 | 0.55 | 0.87 | 18 | empty |
| 3 | 154 | 0.47 | 0.77 | 24 | empty |
| 4 | 95 | 0.38 | 0.76 | 13 | empty |
| 5 | 89 | 0.38 | 0.76 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 1585 Ų buried · 27 hydrogen bonds · protein-protein
Compared structures
- 4ZV6 · Crystal structure of the artificial alpharep-7 octarellinV.1 complex · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 4ZV6 · PDBe 4ZV6
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