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Crystal structure of N-myristoylated mouse mammary tumor virus matrix protein

Analyse Crystal structure of N-myristoylated mouse mammary tumor virus matrix protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4ZV5
Type: protein
Length: 182 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Matrix protein P10
UniProt: P10258
Ligands: MYR
Pockets: 1 · best druggability 0.81

Structure

x-ray diffraction · 1 distinct chain · 70% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Matrix protein P10	protein	91	70% helix, 0% strand	P10258

Ligands and binding sites

MYR · Myristic acid · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	348	0.81	0.90	37	MYR

Interfaces

1 interface between chains.

A–B · 851 Å² buried · 8 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 lipid (myristoylation).

Compared structures

4ZV5 · Crystal structure of N-myristoylated mouse mammary tumor virus matrix protein · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P10258
Elsewhere: RCSB PDB 4ZV5 · PDBe 4ZV5 · UniProt P10258

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