Research workbench
Structure of a fusion protein with a helix linker, 2ARH-3-3KAW-3.0
Analyse Structure of a fusion protein with a helix linker, 2ARH-3-3KAW-3.0 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4ZSZ
- Type
- protein
- Length
- 588 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized fusion protein
- UniProt
- O67778, Q9I208
- Pockets
- 4 · best druggability 0.71
Structure
x-ray diffraction · 1 distinct chain · 56% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Uncharacterized fusion protein | protein | 294 | 56% helix, 16% strand | O67778, Q9I208 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 792 | 0.71 | 0.77 | 71 | empty |
| 2 | 83 | 0.46 | 0.81 | 15 | empty |
| 3 | 57 | 0.41 | 0.81 | 12 | empty |
| 4 | 55 | 0.33 | 0.77 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 1243 Ų buried · 12 hydrogen bonds · protein-protein
Compared structures
- 4ZSZ · Structure of a fusion protein with a helix linker, 2ARH-3-3KAW-3.0 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O67778
- Every structure of UniProt Q9I208
- Elsewhere: RCSB PDB 4ZSZ · PDBe 4ZSZ · UniProt O67778 · UniProt Q9I208
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