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Crystal structure of transporter acrb deletion mutant

Analyse Crystal structure of transporter acrb deletion mutant in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4ZLN
Type: protein
Length: 1,029 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Multidrug efflux pump subunit acrb
UniProt: P31224
Pockets: 14 · best druggability 0.79

Structure

x-ray diffraction · 1 distinct chain · 50% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Multidrug efflux pump subunit acrb	protein	1029	50% helix, 18% strand	P31224

Pockets

14 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	255	0.79	0.92	35	empty
2	696	0.72	0.78	66	empty
3	335	0.69	0.83	51	empty
4	253	0.68	0.84	30	empty
5	193	0.60	0.82	36	empty

Compared structures

4ZLN · Crystal structure of transporter AcrB deletion mutant · the same entry in another collection · chain A against A, TM-score 1.00
P31224 · AlphaFold monomer V2.0 prediction for multidrug efflux pump subunit acrb (P31224) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P31224
Elsewhere: RCSB PDB 4ZLN · PDBe 4ZLN · UniProt P31224

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