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Crystal structure of the glutathione transferase URE2P6 from phanerochaete chrysosporium in complex with oxidized glutathione.

Analyse Crystal structure of the glutathione transferase URE2P6 from phanerochaete… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4ZB8
Type: protein
Length: 220 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: PCURE2P6
Ligands: GDS
Pockets: 1 · best druggability 0.57

Structure

x-ray diffraction · 1 distinct chain · 60% helix, 8% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	PCURE2P6	protein	220	60% helix, 8% strand	—

Ligands and binding sites

GDS · Oxidized glutathione disulfide · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	328	0.57	0.76	40	GDS

Compared structures

4ZB8 · Crystal structure of the glutathione transferase URE2P6 from Phanerochaete chrysosporium… · the same entry in another collection · chain A against A, TM-score 1.00

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Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 4ZB8 · PDBe 4ZB8

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