Research workbench
Phanerochaete chrysosporium URE2P6 in apo form.
Analyse Phanerochaete chrysosporium URE2P6 in apo form. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4ZB7
- Type
- protein
- Length
- 639 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- PCURE2P6
- Ligands
- SO4
- Pockets
- 9 · best druggability 0.54
Structure
x-ray diffraction · 4 distinct chains · 48% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | PCURE2P6 | protein | 171 | 55% helix, 11% strand | — |
| B | PCURE2P6 | protein | 165 | 50% helix, 12% strand | — |
| C | PCURE2P6 | protein | 149 | 43% helix, 13% strand | — |
| D | PCURE2P6 | protein | 154 | 43% helix, 10% strand | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
9 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 227 | 0.54 | 0.77 | 39 | empty |
| 2 | 119 | 0.49 | 0.80 | 17 | empty |
| 3 | 111 | 0.46 | 0.79 | 22 | empty |
| 4 | 154 | 0.43 | 0.74 | 33 | empty |
| 5 | 153 | 0.40 | 0.73 | 29 | empty |
Interfaces
3 interfaces between chains.
- A–B · 1274 Ų buried · 20 hydrogen bonds · protein-protein
- C–D · 1237 Ų buried · 16 hydrogen bonds · protein-protein
- B–C · 290 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 4ZB7 · Phanerochaete chrysosporium URE2P6 in apo form. · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 4ZB7 · PDBe 4ZB7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.