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Crystal structure of the soluble domain of tlpa from bradyrhizobium japonicum
Analyse Crystal structure of the soluble domain of tlpa from bradyrhizobium japonicum in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1JFU
- Type
- protein
- Length
- 353 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- THIOL:DISULFIDE interchange protein tlpa
- UniProt
- P43221
- Pockets
- 2 · best druggability 0.44
Structure
x-ray diffraction · 2 distinct chains · 38% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | THIOL:DISULFIDE interchange protein tlpa | protein | 176 | 38% helix, 22% strand | P43221 |
| B | THIOL:DISULFIDE interchange protein tlpa | protein | 177 | 38% helix, 21% strand | P43221 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 58 | 0.44 | 0.84 | 21 | empty |
| 2 | 59 | 0.27 | 0.73 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 344 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 1JFU · Crystal structure of the soluble domain of tlpa from bradyrhizobium japonicum · the same entry in another collection · chain A against A, TM-score 1.00
- P43221 · AlphaFold monomer V2.0 prediction for THIOL:DISULFIDE interchange protein tlpa (P43221) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P43221
- Elsewhere: RCSB PDB 1JFU · PDBe 1JFU · UniProt P43221
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