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SH3-III of drosophila rim-binding protein bound to a cacophony derived peptide

Analyse SH3-III of drosophila rim-binding protein bound to a cacophony derived peptide in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4Z8A
Type
protein
Length
90 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Rim-binding protein, isoform F; Voltage-dependent calcium channel type a subunit alpha-1
UniProt
A0A0B4JDC9, P91645
Ligands
ACE, NH2

Structure

x-ray diffraction · 2 distinct chains · 12% helix, 30% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARim-binding protein, isoform Fprotein7515% helix, 36% strandA0A0B4JDC9
BVoltage-dependent calcium channel type a subunit alpha-1protein150% helix, 0% strandP91645

Ligands and binding sites

  • ACE · Acetyl group · ligand · chains B
  • NH2 · Amino group · ion · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 742 Ų buried · 12 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 covalent (covalent ligand).

Compared structures

  • 4Z8A · SH3-III of Drosophila Rim-binding protein bound to a Cacophony derived peptide · the same entry in another collection · chain A against A, TM-score 1.00
  • P91645 · AlphaFold monomer V2.0 prediction for voltage-dependent calcium channel type a subunit… · a predicted model of the same protein · chain B against A, TM-score 0.31

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