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The plant peptide hormone receptor in arabidopsis

Analyse The plant peptide hormone receptor in arabidopsis in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4Z63
Type
protein
Length
615 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Phytosulfokine receptor 1; Phytosulfokine
EC
2.7.11.1
UniProt
Q9ZVR7
Ligands
NAG
Pockets
3 · best druggability 0.56

Structure

x-ray diffraction · 2 distinct chains · 18% helix, 22% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APhytosulfokine receptor 1 (EC 2.7.11.1)protein61018% helix, 22% strandQ9ZVR7
PPhytosulfokineprotein50% helix, 40% strand—

Ligands and binding sites

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 9 copies · chains A, P

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12280.560.7929empty
2700.390.7812empty
3590.280.7418empty

Interfaces

1 interface between chains.

  • A–P · 764 Ų buried · 17 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 8 glycan, 5 disulfide, 2 modified (N-glycosylation, disulfide, sulfation).

Compared structures

  • 4Z63 · The plant peptide hormone receptor in arabidopsis · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9ZVR7 · AlphaFold monomer V2.0 prediction for phytosulfokine receptor 1 (Q9ZVR7) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

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