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Avirulence protein 4 (AVR4) from pseudocercospora fuligena

Analyse Avirulence protein 4 (AVR4) from pseudocercospora fuligena in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4Z4A
Type: protein
Length: 149 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Carbohydrate-binding module family 14 protein
Pockets: 1 · best druggability 0.81

Structure

x-ray diffraction · 2 distinct chains · 13% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Carbohydrate-binding module family 14 protein	protein	74	14% helix, 31% strand	—
B	Carbohydrate-binding module family 14 protein	protein	75	13% helix, 36% strand	—

Ligands and binding sites

EDO · 1,2-ethanediol · additive · 16 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	203	0.81	0.95	44	EDO

Interfaces

1 interface between chains.

A–B · 849 Å² buried · 4 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 8 disulfide (disulfide).

Compared structures

4Z4A · Avirulence protein 4 (Avr4) from Pseudocercospora fuligena · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 4Z4A · PDBe 4Z4A

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