Research workbench

Sclerotium rolfsii lectin variant (SSR2) with fine carbohydrate specificity

Analyse Sclerotium rolfsii lectin variant (SSR2) with fine carbohydrate specificity in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4Z2F
Type: protein
Length: 284 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lectin variant 2
Pockets: 4 · best druggability 0.35

Structure

x-ray diffraction · 1 distinct chain · 11% helix, 53% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Lectin variant 2	protein	142	11% helix, 53% strand	—

Ligands and binding sites

MPD · (4S)-2-methyl-2,4-pentanediol · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	84	0.35	0.75	17	empty
2	72	0.33	0.75	16	empty
3	66	0.32	0.76	17	empty
4	61	0.28	0.73	17	empty

Interfaces

1 interface between chains.

A–B · 927 Å² buried · 15 hydrogen bonds · protein-protein

Compared structures

4Z2F · Sclerotium Rolfsii lectin variant (SSR2) with fine carbohydrate specificity · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 4Z2F · PDBe 4Z2F

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