Research workbench
Crystal structure of the extracellular receptor domain of the essential sensor kinase walk from staphylococcus aureus
Analyse Crystal structure of the extracellular receptor domain of the essential sensor… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4YWZ
- Type
- protein
- Length
- 293 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sensor protein kinase walk
- EC
- 2.7.13.3
- UniProt
- Q2YUQ2
- Pockets
- 1 · best druggability 0.74
Structure
x-ray diffraction · 2 distinct chains · 45% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sensor protein kinase walk (EC 2.7.13.3) | protein | 147 | 46% helix, 31% strand | Q2YUQ2 |
| B | Sensor protein kinase walk (EC 2.7.13.3) | protein | 146 | 45% helix, 31% strand | Q2YUQ2 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 224 | 0.74 | 0.89 | 27 | empty |
Interfaces
1 interface between chains.
- A–B · 1087 Ų buried · 15 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 modified (engineered).
Compared structures
- 4YWZ · Crystal structure of the extracellular receptor domain of the essential sensor kinase… · the same entry in another collection · chain A against A, TM-score 1.00
- Q2YUQ2 · AlphaFold monomer V2.0 prediction for sensor protein kinase walk (Q2YUQ2) · a predicted model of the same protein · chain B against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q2YUQ2
- Elsewhere: RCSB PDB 4YWZ · PDBe 4YWZ · UniProt Q2YUQ2
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