Research workbench
X-ray structure of the mutant of glycoside hydrolase
Analyse X-ray structure of the mutant of glycoside hydrolase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4YPJ
- Type
- protein
- Length
- 1,620 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Beta galactosidase
- EC
- 3.2.1.23
- UniProt
- E5RWQ2
- Pockets
- 12 · best druggability 0.76
Structure
x-ray diffraction · 1 distinct chain · 15% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Beta galactosidase (EC 3.2.1.23) | protein | 810 | 15% helix, 40% strand | E5RWQ2 |
Pockets
12 pockets found on a 1 Å grid, 11 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 999 | 0.76 | 0.78 | 87 | empty |
| 2 | 73 | 0.76 | 0.99 | 21 | empty |
| 3 | 75 | 0.75 | 0.98 | 23 | empty |
| 4 | 1045 | 0.75 | 0.78 | 89 | empty |
| 5 | 1046 | 0.73 | 0.76 | 105 | empty |
Interfaces
1 interface between chains.
- A–B · 652 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 4YPJ · X-ray Structure of The Mutant of Glycoside Hydrolase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt E5RWQ2
- Elsewhere: RCSB PDB 4YPJ · PDBe 4YPJ · UniProt E5RWQ2
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