Research workbench

Tubulin glutamylase

Analyse Tubulin glutamylase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4YLS
Type: protein
Length: 331 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tubulin polyglutamylase TTLL7
EC: 6.-.-.-
UniProt: Q6ZT98
Ligands: ANP
Pockets: 3 · best druggability 0.38

Structure

x-ray diffraction · 1 distinct chain · 37% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tubulin polyglutamylase TTLL7 (EC 6.-.-.-)	protein	331	37% helix, 25% strand	Q6ZT98

Ligands and binding sites

ANP · Phosphoaminophosphonic acid-adenylate ester · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	73	0.38	0.78	14	ANP
2	77	0.32	0.74	16	empty
3	53	0.30	0.76	14	empty

Compared structures

4YLS · Tubulin Glutamylase · the same entry in another collection · chain A against A, TM-score 1.00
Q6ZT98 · AlphaFold monomer V2.0 prediction for tubulin polyglutamylase TTLL7 (Q6ZT98) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6ZT98
Elsewhere: RCSB PDB 4YLS · PDBe 4YLS · UniProt Q6ZT98

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