Research workbench
Crystal structure of the ATG101-ATG13 complex from fission yeast
Analyse Crystal structure of the ATG101-ATG13 complex from fission yeast in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4YK8
- Type
- protein
- Length
- 356 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Meiotically up-regulated gene 66 protein; Autophagy protein 13
- UniProt
- O13978, O36019
- Pockets
- 5 · best druggability 0.58
Structure
x-ray diffraction · 2 distinct chains · 35% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Meiotically up-regulated gene 66 protein | protein | 162 | 35% helix, 27% strand | O13978 |
| B | Autophagy protein 13 | protein | 194 | 35% helix, 22% strand | O36019 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 299 | 0.58 | 0.77 | 32 | empty |
| 2 | 88 | 0.39 | 0.77 | 17 | empty |
| 3 | 63 | 0.32 | 0.74 | 13 | empty |
| 4 | 53 | 0.29 | 0.75 | 15 | empty |
| 5 | 60 | 0.28 | 0.74 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 1179 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
- 4YK8 · Crystal structure of the Atg101-Atg13 complex from fission yeast · the same entry in another collection · chain A against A, TM-score 1.00
- O36019 · AlphaFold monomer V2.0 prediction for autophagy protein 13 (O36019) · a predicted model of the same protein · chain B against A, TM-score 0.92
- O13978 · AlphaFold monomer V2.0 prediction for meiotically up-regulated gene 66 protein (O13978) · a predicted model of the same protein · chain A against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O13978
- Every structure of UniProt O36019
- Elsewhere: RCSB PDB 4YK8 · PDBe 4YK8 · UniProt O13978 · UniProt O36019
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