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Crystal structure of hiran domain of human hltf in complex with DNA

Analyse Crystal structure of hiran domain of human hltf in complex with DNA in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4XZF
Type
protein + DNA
Length
134 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
(DA)(DC)(DC)(DG)(DC)(DC)(DG)(DG)(DG)(DT)(DG)(DC)(DC); Helicase-like transcription factor
EC
3.6.4.-, 6.3.2.-
UniProt
Q14527

Structure

x-ray diffraction · 2 distinct chains · 23% helix, 36% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
B(DA)(DC)(DC)(DG)(DC)(DC)(DG)(DG)(DG)(DT)(DG)(DC)(DC)dna13——
AHelicase-like transcription factor (EC 3.6.4.-, 6.3.2.-)protein12123% helix, 36% strandQ14527

Interfaces

1 interface between chains.

  • B–A · 357 Ų buried · 7 hydrogen bonds · protein-nucleic

Compared structures

  • 4XZF · Crystal structure of HIRAN domain of human HLTF in complex with DNA · the same entry in another collection · chain B against B, TM-score 1.00
  • Q14527 · AlphaFold monomer V2.0 prediction for helicase-like transcription factor (Q14527) · a predicted model of the same protein · chain A against A, TM-score 0.97

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