Research workbench
Oxyr regulatory domain C199D mutant from pseudomonas aeruginosa
Analyse Oxyr regulatory domain C199D mutant from pseudomonas aeruginosa in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4XWS
- Type
- protein
- Length
- 789 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Oxyr
- UniProt
- Q9HTL4
- Pockets
- 10 · best druggability 0.75
Structure
x-ray diffraction · 4 distinct chains · 27% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Oxyr | protein | 212 | 25% helix, 28% strand | Q9HTL4 |
| B | Oxyr | protein | 192 | 27% helix, 29% strand | Q9HTL4 |
| C | Oxyr | protein | 191 | 28% helix, 30% strand | Q9HTL4 |
| D | Oxyr | protein | 194 | 30% helix, 30% strand | Q9HTL4 |
Pockets
10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 700 | 0.75 | 0.81 | 90 | empty |
| 2 | 490 | 0.71 | 0.81 | 57 | empty |
| 3 | 497 | 0.66 | 0.78 | 48 | empty |
| 4 | 232 | 0.51 | 0.76 | 26 | empty |
| 5 | 143 | 0.49 | 0.78 | 24 | empty |
Interfaces
4 interfaces between chains.
- A–B · 1126 Ų buried · 7 hydrogen bonds · protein-protein
- C–D · 1105 Ų buried · 4 hydrogen bonds · protein-protein
- A–D · 335 Ų buried · 1 hydrogen bond · protein-protein
- B–D · 48 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 4XWS · OxyR regulatory domain C199D mutant from pseudomonas aeruginosa · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HTL4
- Elsewhere: RCSB PDB 4XWS · PDBe 4XWS · UniProt Q9HTL4
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