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Crystal structure of (GCCU(G-LNA)CCUGC)2 duplex

Analyse Crystal structure of (GCCU(G-LNA)CCUGC)2 duplex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4XW0
Type
RNA
Length
19 nucleotides
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
RNA (5'-R(*GP*CP*CP*UP*(LCG)P*CP*CP*UP*GP*C)-3')
Ligands
SO4

Structure

x-ray diffraction · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
ARNA (5'-R(*GP*CP*CP*UP*(LCG)P*CP*CP*UP*GP*C)-3')rna10——
BRNA (5'-R(*GP*CP*CP*UP*(LCG)P*CP*CP*UP*GP*C)-3')rna9——

Ligands and binding sites

  • SO4 · Sulfate ion · ion · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 340 Ų buried · 30 hydrogen bonds · nucleic-nucleic

Modifications

Observed in the structure: 2 modified (nucleotide modification).

Compared structures

  • 4XW0 · Crystal structure of (GCCU(G-LNA)CCUGC)2 duplex · the same entry in another collection · chain A against A, TM-score 1.00

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