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Crystal structure of importin beta in an ammonium sulfate condition

Analyse Crystal structure of importin beta in an ammonium sulfate condition in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4XRI
Type: protein
Length: 865 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative uncharacterized protein
UniProt: G0S143
Ligands: SO4
Pockets: 8 · best druggability 0.62

Structure

x-ray diffraction · 1 distinct chain · 79% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative uncharacterized protein	protein	865	79% helix, 0% strand	G0S143

Ligands and binding sites

SO4 · Sulfate ion · ion · 9 copies · chains A
GOL · Glycerol · additive · 9 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

8 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	316	0.62	0.79	30	empty
2	104	0.41	0.77	18	GOL
3	67	0.39	0.79	14	empty
4	121	0.38	0.74	19	empty
5	93	0.37	0.76	20	GOL

Compared structures

4XRI · Crystal Structure of Importin Beta in an Ammonium Sulfate Condition · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt G0S143
Elsewhere: RCSB PDB 4XRI · PDBe 4XRI · UniProt G0S143

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