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Structure of chlamydomonas reinhardtii THB1

Analyse Structure of chlamydomonas reinhardtii THB1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4XDI
Type: protein
Length: 250 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Chlamydomonas reinhardtii THB1
UniProt: A8JAR4
Ligands: HEM
Pockets: 2 · best druggability 0.77

Structure

x-ray diffraction · 2 distinct chains · 69% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Chlamydomonas reinhardtii THB1	protein	127	67% helix, 1% strand	A8JAR4
B	Chlamydomonas reinhardtii THB1	protein	123	72% helix, 1% strand	A8JAR4

Ligands and binding sites

HEM · Protoporphyrin IX containing Fe · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	350	0.77	0.87	38	HEM
2	390	0.75	0.85	41	HEM

Interfaces

1 interface between chains.

A–B · 672 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

4XDI · Structure of Chlamydomonas reinhardtii THB1 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A8JAR4
Elsewhere: RCSB PDB 4XDI · PDBe 4XDI · UniProt A8JAR4

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