Research workbench
Crystal structure of semisweet in the inward-open and outward-open conformations
Analyse Crystal structure of semisweet in the inward-open and outward-open conformations in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4X5N
- Type
- protein
- Length
- 366 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein
- UniProt
- T8UDF6
- Pockets
- 4 · best druggability 0.81
Structure
x-ray diffraction · 4 distinct chains · 85% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized protein | protein | 91 | 85% helix, 0% strand | T8UDF6 |
| B | Uncharacterized protein | protein | 92 | 86% helix, 0% strand | T8UDF6 |
| C | Uncharacterized protein | protein | 92 | 83% helix, 0% strand | T8UDF6 |
| D | Uncharacterized protein | protein | 91 | 86% helix, 0% strand | T8UDF6 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 773 | 0.81 | 0.84 | 52 | empty |
| 2 | 401 | 0.69 | 0.81 | 38 | empty |
| 3 | 374 | 0.62 | 0.76 | 28 | empty |
| 4 | 67 | 0.33 | 0.75 | 13 | empty |
Interfaces
3 interfaces between chains.
- C–D · 1530 Ų buried · 6 hydrogen bonds · protein-protein
- A–B · 1530 Ų buried · 14 hydrogen bonds · protein-protein
- A–D · 270 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 4X5N · Crystal structure of SemiSWEET in the inward-open and outward-open conformations · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt T8UDF6
- Elsewhere: RCSB PDB 4X5N · PDBe 4X5N · UniProt T8UDF6
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.