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Active-site mutant of rhizomucor miehei beta-1,3-glucanosyltransferase in complex with laminaritriose

Analyse Active-site mutant of rhizomucor miehei beta-1,3-glucanosyltransferase in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4WTS
Type: protein
Length: 266 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Beta-1,3-glucanosyltransferase
EC: 2.4.1.-
Ligands: BGC
Pockets: 3 · best druggability 0.60

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Beta-1,3-glucanosyltransferase (EC 2.4.1.-)	protein	266	42% helix, 17% strand	—

Ligands and binding sites

BGC · beta-D-glucopyranose · sugar · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	328	0.60	0.77	28	BGC
2	68	0.39	0.79	19	empty
3	60	0.39	0.80	19	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

4WTS · Active-site mutant of Rhizomucor miehei beta-1,3-glucanosyltransferase in complex with… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 4WTS · PDBe 4WTS

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