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The C-terminal domain of gene product LPG0944 from legionella pneumophila subsp. pneumophila str. philadelphia 1

Analyse The C-terminal domain of gene product LPG0944 from legionella pneumophila… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4WRP
Type: protein
Length: 236 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uncharacterized protein
UniProt: Q5ZWY9
Pockets: 3 · best druggability 0.53

Structure

x-ray diffraction · 2 distinct chains · 60% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Uncharacterized protein	protein	121	60% helix, 1% strand	Q5ZWY9
B	Uncharacterized protein	protein	115	61% helix, 1% strand	Q5ZWY9

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	137	0.53	0.81	27	empty
2	128	0.40	0.75	19	empty
3	115	0.39	0.74	17	empty

Interfaces

1 interface between chains.

A–B · 803 Å² buried · 13 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 modified (engineered).

Compared structures

4WRP · The C-terminal domain of gene product lpg0944 from Legionella pneumophila subsp.… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5ZWY9
Elsewhere: RCSB PDB 4WRP · PDBe 4WRP · UniProt Q5ZWY9

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