Research workbench
Chaetomium thermophilum MEX67 NTF2-like domain complexed with MTR2
Analyse Chaetomium thermophilum MEX67 NTF2-like domain complexed with MTR2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4WP5
- Type
- protein
- Length
- 370 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- MRNA export protein; MTR2
- UniProt
- G0SET4, G0SG92
- Pockets
- 3 · best druggability 0.41
Structure
x-ray diffraction · 2 distinct chains · 26% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | MRNA export protein | protein | 199 | 22% helix, 37% strand | G0SET4 |
| B | MTR2 | protein | 171 | 30% helix, 35% strand | G0SG92 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 143 | 0.41 | 0.74 | 23 | empty |
| 2 | 137 | 0.40 | 0.74 | 31 | empty |
| 3 | 58 | 0.29 | 0.74 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 1999 Ų buried · 33 hydrogen bonds · protein-protein
Compared structures
- 4WP5 · Chaetomium thermophilum Mex67 NTF2-like domain complexed with Mtr2 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G0SET4
- Every structure of UniProt G0SG92
- Elsewhere: RCSB PDB 4WP5 · PDBe 4WP5 · UniProt G0SET4 · UniProt G0SG92
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